In 2012, Moseley was asked to research fasting for a BBC documentary, including trying the idea himself. He was in his fifties. Researchers he met with included Prof. Luigi Fontana of Washington University School of Medicine, Dr. Krista Varady of the Univ. of Illinois, and Prof. Mark Matteson. He was not particularly looking forward to the idea of fasting for 3 days and 4 nights. However, the changes were significant enough (at 33 minute mark in the BBC documentary) that after going home he experimented with the fasting for five weeks based on the 5-2 approach. The results were similar to the 4-day fast (52 min mark). His first book about the "Fast Diet" came out in 2013 and became a NY Times best seller; it was updated in 2015.
The BBC documentary is an hour and well worth watching. For a shorter introduction, check out report below by an Australian journalist who traveled to meet Moseley in 2014.
5 2 Diet, 16 min - 2014
https://youtu.be/VWtaLLjJzn4
Eat, Fast & Live Longer BBC Documentary, 1 hr, created 2012, posted 2015
https://youtu.be/Ihhj_VSKiTs
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